Robustness of Column Selection to Mobile Phase Changes for the Aggregate Analysis of AAV Capsids

Biozen dSEC-7 proves instrumental in quickly and accurately resolving AAV monomer from aggregates in under 10 minutes, showcasing consistent results across different mobile phase conditions. With a 700 Å pore size and patented hydrophilic diol-type surface chemistry, this SEC column ensures excellent resolution and recovery for AAV serotypes 5, 8, and 9. This flexible approach to method development offers a reliable and reproducible solution for AAV aggregate quantitation.